I used to do ALL my art the "old fashioned" way... pecils, markers, airbrush and acrylic paint. But once I got good at Photoshop, I liked it so much that I never went back to the old way.
At first it felt very weird to me... when drawing or painting in Photoshop you don't get the tactile sensation that you get by running a pencil or brush across paper... it's really a totally different feeling, and one that's quite weird until you get used to it. I didn't like it at all at first, but since my business is graphic design and illustration, I HAD to make the switch to digital, because that's the way the industry went. But now that I've gotten pretty good with Photoshop, I like it! No more clogged airbrushes! And I save a fortune in paint! Plus I never run out of a color right in the middle of something...