I read on another site a number of years ago that you really must use gloves with Super Clean, The thinking at the time was that there was a chemical in the Super Clean that will attack a person's liver. Whether this is correct or not, I will leave to each person to figure out. But I always use a thicker pair of gloves and would not trust nitrile gloves. I am not going to ruin my health over a hobby and I encourage others to use the same level of caution. As far as disposing this stuff, NEVER, EVER put it down the drain. While the Super Clean or Purple Power may be harmless, the paint is not. I put the stuff that I am not using anymore in its original container, label it and take it to the chemical disposal facility.