Spray cans? Heck yeah! Tamiya is the way to go. (To be fair, I have not tried Testors lacquers) Like the other guys said, warm up the can first. For a base coat, your imagination is the only limit. I tried to make a candy burgundy by spraying Tamiya red over Tamiya dark grey (a military shade, also in a can). That was before I found out that burgundy is really purple with very little blue in it. It turned out nice, though.
If you do a two-tone paint job, use Tamiya masking tape. It is very thin and holds a really clean line.