I'm diabetic and have never seen quantities less than 100 ... when you use 4 or 5 a day, that's a small supply. Having gotten a Medical Discharge for diabetes, I get all mine free from the VA, so I don't even know if the average person can just walk in and buy any without a prescription. Most of the ones I get are 29 or 30 gage. I have tried them for CA but got only one use since it hardened inside ... maybe I needed to flush better or suck in some debonder. The hundred pack may be a good buy it that happens often. I just went back to toothpicks and sewing needles.