I'd never take the NYC route. I am leaving from Western Mass, so maybe I have a slight advantage. But, my wife grew up in Wayne so I have been making this trip for 35 years. Best, IMO, is to just take the Mass Pike straight to the NY Thruway and go down from there. You can also take your route thru Hartford, (my hometown) and take 84 to the Thruway. I know it seems it should be faster taking the angle route thru NYC, but it never worked for me. There's just too many slowdowns and slower roads along the way. The thruway traffic has been moving at 80mph average lately, just like the Mass Pike. Either way, get on the Garden State Parkway and find your exit off there. I'm not giving directions there as I take all the local shortcuts and never even hit the Parkway. I have to say, though, Route 17 and 46 are the worst traffic roads in the world. All the malls and shopping centers are along these routes. 46 isn't that bad to drive and you'll have to hit that I think as it's close to everything. Just keep on highways as far as you possibly can. The Parkway pretty much follows 17 in this area.
Hope to see ya there.